A randomized, placebo-controlled trial of AFQ056 for the treatment of chorea in Huntington's disease.
Identifieur interne : 000341 ( Main/Exploration ); précédent : 000340; suivant : 000342A randomized, placebo-controlled trial of AFQ056 for the treatment of chorea in Huntington's disease.
Auteurs : Ralf Reilmann [Allemagne] ; Marie-Laure Rouzade-Dominguez ; Carsten Saft ; Sigurd D. Süssmuth ; Josef Priller ; Anne Rosser ; Hugh Rickards ; Ludger Schöls ; Nicole Pezous ; Fabrizio Gasparini ; Donald Johns ; Georg Bernhard Landwehrmeyer ; Baltazar Gomez-MancillaSource :
- Movement disorders : official journal of the Movement Disorder Society [ 1531-8257 ] ; 2015.
Abstract
This study investigated the hypothesis that AFQ056 (mavoglurant), a selective metabotropic glutamate receptor 5 antagonist, reduces chorea in Huntington's disease (HD).
DOI: 10.1002/mds.26174
PubMed: 25689146
Affiliations:
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Süssmuth</name></noCountry><country name="Allemagne"><region name="Bade-Wurtemberg"><name sortKey="Reilmann, Ralf" sort="Reilmann, Ralf" uniqKey="Reilmann R" first="Ralf" last="Reilmann">Ralf Reilmann</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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